Results published by Investigator on non-invasive assessment of c-MET expression in non-small cell lung cancer

1 Mar 2023 | [Ga-68]EMP-100, Collaborations

A case of a 56-year-old female former smoker with stage IV EGFR mutation-positive NSCLC (lymphogenic, pulmonary, hepatic, and cerebral metastases is presented. Stage: cT3, cN3, cM1b) and concomitant MET exon 14 skipping mutation. After multiple pretreatments including...

Results published by Investigator on identification and validation of MET as target for fluorescent guided surgery in papillary thyroid cancer

11 Apr 2022 | Collaborations, EMI-137

Patients undergoing prophylactic central compartment dissection (PCLND) for papillary thyroid cancer (PTC) are often overtreated. This study aimed to determine if molecular fluorescence-guided imaging (MFGI) and spectroscopy can be useful for detecting PTC nodal...

Results published by Investigator on first-in-human biodistribution and first PET imaging results of [Ga-68]EMP-100 in metastatic renal cell carcinoma

6 Dec 2021 | [Ga-68]EMP-100, Collaborations

This first in‑human biodistribution and imaging study for 68Ga‑EMP‑100 in metastatic renal cell carcinoma independently carried out by LMU Munich, Germany, evaluated uptake characteristics in metastases and primary RCC. Conclusion: Visualization of c-MET expression...

Results published by Investigator on Image-guided Surgery in Penile Squamous Cell Carcinoma Patients

21 May 2021 | Collaborations, EMI-137

This pilot study suggest that c-MET is a promising target for fluorescence-guided tumour identification, with the potential to improve margin assessment in pSCC. The c-MET targeted approach proved to be compatible with lymphatic mapping performed in the same patient...

Results from Phase II clinical development of EMI-137 published

2 Oct 2020 | EMI-137

The work carried ou as part of Phase IIb stage of development of EMI-137 has showed FME using EMI-137 appeared to be safe andfeasible within a 1- to 3-h dose-to-imaging interval. No clinicallysignificant differences were observed among the cohorts, althougha 1-h...